Analysis of Drug Substances in Common Cold Medicines with the PerkinElmer Flexar FX-15 System Equipped with a PDA Detector
ثبت نشده
چکیده
The common cold is a frequent upper respiratory tract infection caused by a number of different types of viruses. Common cold affects billions of people worldwide every year; its typical symptoms include a runny nose, nasal congestion and sneezing. Colds can also cause sore throat, cough and headache. Common cold viruses do not respond to antibiotics and there are no known cures. Although the symptoms are normally resolved within ten days, they can cause a great deal of discomfort. Fortunately, these symptoms can be alleviated by the use of over-the-counter medicines. These cold remedies invariably include acetaminophen (a pain reliever and fever reducer), a cough suppressant (antitussive) and a nasal decongestant. Commonly used antitussive and nasal decongestant are dextromethorphan HBr and phenylephrine HCL. Dextromethorphan temporarily relieves cough by decreasing activity in the part of the brain that causes the coughing. Phenylephrine relieves nasal discomfort and sinus congestion by reducing the swelling of blood vessels in the nasal passages. Since they don’t treat the underlying cause of the illness, cold medicines do not necessarily speed the recovery. UHPLC a p p l i c a t i o n n o t e
منابع مشابه
Determination of Ginsenosides in Ginseng Root Powder by Flexar LC/PDA and Flexar SQ 300 MS Detector
The root of the ginseng plants has been used as herbal medicine in Asia for over two thousand years. It is purported to possess antioxidant, anticarcinogenic, anti-inflammatory, antihypertensive and anti-diabetic properties. The pharmacologically active compounds behind the claims of ginseng's efficacy are ginsenosides; their underlying mechanism of action, although not entirely elucidated, app...
متن کاملEvaluation of Residual Diazinon and Chlorpiryfos in Children Herbal Medicines by Headspace-SPME and GC-FID
AbstractThe oldest method for the managing of the illness is the use of medicinal plants. The use of herbal products as the first choice in self-treatment of minor conditions continues to expand rapidly across Iran. This makes the safety of herbal products an important public health issue.Pesticides are used widely in agriculture to increase the production by controlling the harmful insects and...
متن کاملEvaluation of Residual Diazinon and Chlorpiryfos in Children Herbal Medicines by Headspace-SPME and GC-FID
AbstractThe oldest method for the managing of the illness is the use of medicinal plants. The use of herbal products as the first choice in self-treatment of minor conditions continues to expand rapidly across Iran. This makes the safety of herbal products an important public health issue.Pesticides are used widely in agriculture to increase the production by controlling the harmful insects and...
متن کاملComponent Analysis of the Illegal Handmade Pills and Capsules for Self-Medicating Substance Dependence in Tehran, Iran
Background: To self-medicate substance dependence, many substance users consume herbal medicines delivered in herbal medicine shops which are prepared through non-standard methods using a variety of different materials. Hence, the present study was carried out aiming to investigate and analyze the content of such herbal medicines.Methods: Four herbal medicine shops were selected from each of th...
متن کاملAcute Poisoning in Elderly; a Five-Year Study (2008-2013) in Hamadan, Iran
Background: A good proportion of poisoned patients treated at poisoning wards are elderly. This study was designed to evaluate the epidemiologic pattern of acute poisoning in elderly in Hamadan, western Iran. Methods: In this retrospective cross-sectional study, poisoned patients aged 60 years and older treated at department of poisoning of Farshchian Hospital from March 2008 to March 2013 wer...
متن کامل